by David P Hill, Barry Smith, Monica S McAndrews-Hill, Judith A. Blake
Abstract:
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). Here we address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations, in the hope that this will lead both to better representations of biological reality through annotation and ontology development and to more informed use of GO resources by experimental scientists.
Reference:
Gene Ontology annotations: what they mean and where they come from. (David P Hill, Barry Smith, Monica S McAndrews-Hill, Judith A. Blake), In BMC Bioinformatics, volume 9 Suppl 5, 2008.
Bibtex Entry:
@article{Hill2008,
abstract = {To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). Here we address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations, in the hope that this will lead both to better representations of biological reality through annotation and ontology development and to more informed use of GO resources by experimental scientists.},
author = {Hill, David P and Smith, Barry and McAndrews-Hill, Monica S and Blake, Judith A.},
doi = {10.1186/1471-2105-9-S5-S2},
issn = {1471-2105},
journal = {BMC Bioinformatics},
keywords = {Animals,Artificial Intelligence,Computational Biology,Computational Biology: methods,Computational Biology: standards,Database Management Systems,Database Management Systems: organization \& admini,Database Management Systems: standards,Databases, Genetic,Databases, Genetic: trends,Genomics,Genomics: organization \& administration,Genomics: standards,Humans,Models, Biological,Pattern Recognition, Automated,Pattern Recognition, Automated: methods,Pattern Recognition, Automated: trends,SML-LIB-BIBLIO,Semantics,Systems Integration,User-Computer Interface,Vocabulary, Controlled,lang:ENG},
mendeley-tags = {SML-LIB-BIBLIO,lang:ENG},
month = jan,
pages = {S2},
pmid = {18460184},
title = {{Gene Ontology annotations: what they mean and where they come from.}},
url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2367625\&tool=pmcentrez\&rendertype=abstract},
volume = {9 Suppl 5},
year = {2008}
}