by Anthony Ml Liekens, Jeroen De Knijf, Walter Daelemans, Bart Goethals, Peter De Rijk, Jurgen Del-Favero
Abstract:
ABSTRACT: We present BioGraph, a data integration and data mining platform for the exploration and discovery of biomedical information. The platform offers prioritizations of putative disease genes, supported by functional hypotheses. We show that BioGraph can retrospectively confirm recently discovered disease genes and identify potential susceptibility genes, outperforming existing technologies, without requiring prior domain knowledge. Additionally, BioGraph allows for generic biomedical applications beyond gene discovery. BioGraph is accessible at http://www.biograph.be.
Reference:
BioGraph: Unsupervised biomedical knowledge discovery via automated hypothesis generation. (Anthony Ml Liekens, Jeroen De Knijf, Walter Daelemans, Bart Goethals, Peter De Rijk, Jurgen Del-Favero), In Genome biology, BioMed Central Ltd, volume 12, 2011.
Bibtex Entry:
@article{Liekens2011,
abstract = {ABSTRACT: We present BioGraph, a data integration and data mining platform for the exploration and discovery of biomedical information. The platform offers prioritizations of putative disease genes, supported by functional hypotheses. We show that BioGraph can retrospectively confirm recently discovered disease genes and identify potential susceptibility genes, outperforming existing technologies, without requiring prior domain knowledge. Additionally, BioGraph allows for generic biomedical applications beyond gene discovery. BioGraph is accessible at http://www.biograph.be.},
author = {Liekens, Anthony Ml and {De Knijf}, Jeroen and Daelemans, Walter and Goethals, Bart and {De Rijk}, Peter and Del-Favero, Jurgen},
doi = {10.1186/gb-2011-12-6-r57},
issn = {1465-6914},
journal = {Genome biology},
keywords = {SML-LIB-BIBLIO,lang:ENG},
mendeley-tags = {SML-LIB-BIBLIO,lang:ENG},
month = jun,
number = {6},
pages = {R57},
pmid = {21696594},
publisher = {BioMed Central Ltd},
title = {{BioGraph: Unsupervised biomedical knowledge discovery via automated hypothesis generation.}},
url = {http://www.ncbi.nlm.nih.gov/pubmed/21696594},
volume = {12},
year = {2011}
}