Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

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by Michael Ashburner, Catherine A. Ball, Judith A. Blake, David Botstein, Heather Butler, ...
Abstract:
Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the biological role of such shared proteins in one organism can often be transferred to other organisms. The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing. To this end, three independent ontologies accessible on the World-Wide Web are being constructed: biological process, molecular function and cellular component.
Reference:
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. (Michael Ashburner, Catherine A. Ball, Judith A. Blake, David Botstein, Heather Butler, ...), In Nature Genetics, Nature Publishing Group, volume 25, 2000.
Bibtex Entry:
@article{Ashburner2000,
abstract = {Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the biological role of such shared proteins in one organism can often be transferred to other organisms. The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing. To this end, three independent ontologies accessible on the World-Wide Web are being constructed: biological process, molecular function and cellular component.},
annote = {
        From Duplicate 2 ( 
        
        
          Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
        
        
         - Ashburner, M; Ball, C A; Blake, J A; Botstein, D; Butler, H; Cherry, J M; Davis, A P; Dolinski, K; Dwight, S S; Eppig, J T; Harris, M A; Hill, David P; Issel-Tarver, L; Kasarskis, A; Lewis, S; Matese, J C; Richardson, J E; Ringwald, M; Rubin, G M; Sherlock, G )
And  Duplicate 3 ( 
        
        
          Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
        
        
         - Ashburner, M; Ball, C A; Blake, J A; Botstein, D; Butler, H; Cherry, J M; Davis, A P; Dolinski, K; Dwight, S S; Eppig, J T; Harris, M A; Hill, David P; Issel-Tarver, L; Kasarskis, A; Lewis, S; Matese, J C; Richardson, J E; Ringwald, M; Rubin, G M; Sherlock, G )

        
        

        

        

      },
author = {Ashburner, Michael and Ball, Catherine A. and Blake, Judith A. and Botstein, David and Butler, Heather and ...},
doi = {10.1038/75556},
institution = {Department of Genetics, Stanford University School of Medicine, California, USA. cherry@stanford.edu},
issn = {10614036},
journal = {Nature Genetics},
keywords = {SML-LIB-BIBLIO,animals,biohackathon2010 data-mining,computer communication networks,databases,dna,eukaryotic cells,eukaryotic cells physiology,factual,genes,genetics,genome,humans,lang:ENG,metaphysics,mice,molecular biology,molecular biology trends,ontology,protein,proteomics,sequence analysis,terminology topic},
mendeley-tags = {SML-LIB-BIBLIO,biohackathon2010 data-mining,databases,genetics,genome,lang:ENG,ontology,protein,proteomics},
month = may,
number = {1},
pages = {25--29},
pmid = {10802651},
publisher = {Nature Publishing Group},
title = {{Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.}},
type = {Journal article},
url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037419/ http://www.ncbi.nlm.nih.gov/pubmed/10802651},
volume = {25},
year = {2000}
}
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