by David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry, Bernard Jacq
Abstract:
We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.
Reference:
GOToolBox: functional analysis of gene datasets based on Gene Ontology. (David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry, Bernard Jacq), In Genome biology, volume 5, 2004.
Bibtex Entry:
@article{Martin2004,
abstract = {We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.},
author = {Martin, David and Brun, Christine and Remy, Elisabeth and Mouren, Pierre and Thieffry, Denis and Jacq, Bernard},
doi = {10.1186/gb-2004-5-12-r101},
issn = {1465-6914},
journal = {Genome biology},
keywords = {Animals,Databases, Genetic,Drosophila melanogaster,Drosophila melanogaster: genetics,Genomics,Genomics: methods,Internet,Protein Interaction Mapping,SML-LIB-BIBLIO,Software,lang:ENG},
mendeley-tags = {SML-LIB-BIBLIO,lang:ENG},
month = jan,
number = {12},
pages = {R101},
pmid = {15575967},
title = {{GOToolBox: functional analysis of gene datasets based on Gene Ontology.}},
url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=545796\&tool=pmcentrez\&rendertype=abstract},
volume = {5},
year = {2004}
}