by Andreas Schlicker, Jörg Rahnenführer, Mario Albrecht, Thomas Lengauer, Francisco S. Domingues
Abstract:
We describe GOTax, a comparative genomics platform that integrates protein annotation with protein family classification and taxonomy. User-defined sets of proteins, protein families, annotation terms or taxonomic groups can be selected and compared, allowing for the analysis of distribution of biological processes and molecular activities over different taxonomic groups. In particular, a measure of functional similarity is available for comparing proteins and protein families, establishing functional relationships independent of evolution.
Reference:
GOTax: investigating biological processes and biochemical activities along the taxonomic tree. (Andreas Schlicker, Jörg Rahnenführer, Mario Albrecht, Thomas Lengauer, Francisco S. Domingues), In Genome biology, volume 8, 2007.
Bibtex Entry:
@article{Schlicker2007,
abstract = {We describe GOTax, a comparative genomics platform that integrates protein annotation with protein family classification and taxonomy. User-defined sets of proteins, protein families, annotation terms or taxonomic groups can be selected and compared, allowing for the analysis of distribution of biological processes and molecular activities over different taxonomic groups. In particular, a measure of functional similarity is available for comparing proteins and protein families, establishing functional relationships independent of evolution.},
author = {Schlicker, Andreas and Rahnenf\"{u}hrer, J\"{o}rg and Albrecht, Mario and Lengauer, Thomas and Domingues, Francisco S.},
doi = {10.1186/gb-2007-8-3-r33},
issn = {1465-6914},
journal = {Genome biology},
keywords = {Classification,Databases, Nucleic Acid,Genomics,Information Storage and Retrieval,Phylogeny,Proteomics,Proteomics: methods,SML-LIB-BIBLIO,Software,User-Computer Interface,lang:ENG},
mendeley-tags = {SML-LIB-BIBLIO,lang:ENG},
month = jan,
number = {3},
pages = {R33},
pmid = {17346342},
title = {{GOTax: investigating biological processes and biochemical activities along the taxonomic tree.}},
url = {http://genomebiology.com/2007/8/3/R33},
volume = {8},
year = {2007}
}